A Case of Macrophagic Activation Syndrome in a Child with Epilepsy Treated with an Excessive Dose of Sodium Valproate
Published: August 1, 2020 | DOI: https://doi.org/10.7860/JCDR/2020/44447.13950
Kambourou Judicael, Moyen-Engoba, Oko Aymar Pierre Gildas, Lethso Thibaut Ocko Gokaba, Olivia Firmine Atipo Galiba
1. Lecturer, Department of Paediatrics, Faculty of Health Sciences, University Marien NGOUABI, Brazzaville, Congo.
2. Lecturer, Departement of Paediatrics, University Hospital, Brazzaville, Congo.
3. Lecturer, Departement of Paediatrics, University Hospital, Brazzaville, Congo.
4. Lecturer, Departement of Biological Hematology, University Hospital, Brazzaville, Congo.
5. Department of Clinical Hematology, University Hospital, Brazzaville, Congo.
Correspondence
Dr. Kambourou Judicael,
Lecturer, Department of Paediatrics, Faculty of Health Sciences, University Marien NGOUABI, Brazzaville, Congo.
E-mail: judycokam@yahoo.fr
Macrophagic Activation Syndrome (MAS) is a rare disorder and is thought to result from non-malignant activation and proliferation of macrophages and T-cells. It can be of primary or secondary origin and its prognosis is often poor. Authors report a case of a three-year-old boy admitted in the intensive care unit for MAS secondary to an overdose of sodium valproate to remind practitioners to think about it in the presence of a febrile pancytopenia.
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